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℡ 4000-520-616
℡ 4000-520-616
ApexBio/Human Angiopoietin 4 / ANG4 / ANGPT4 Protein (His Tag)/50ug/G1004
产品编号:G1004
市  场 价:¥7200.00
场      地:美国(厂家直采)
产品分类: 蛋白类>聚合物>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$360.00
品      牌: ApexBio
公      司:ApexBio
公司分类:
ApexBio/Human Angiopoietin 4 / ANG4 / ANGPT4 Protein (His Tag)/50ug/G1004
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Human Angiopoietin 4 / ANG4 / ANGPT4 Protein (His Tag)

Catalog No.G1004
SizePriceStockQty
50ug
$360.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Publications citing ApexBio Products

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Cell.Available online 25 October 2018.
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Cell.2018 Feb 22;172(5):1007-1021.e17.
Cell.2017 Nov 30;171(6):1284-1300.e21.
Cell.2017 Aug 17. pii: S0092-8674(17)30869-3.
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Description

Synonym ANGPT4, ANG3, ANG4
Protein Construction A DNA sequence encoding the human ANGPT4 (NP_068769.2) (Met282-Ile503) was expressed, with an N-terminal polyhistidine tag.
Source Human
Expression Host Human Cells
Purity >80 % as determined by SDS-PAGE
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method
Stability Samples are stable for up to twelve months from date of receipt at -70℃
Predicted N terminal His
Molecular Mass The recombinant human ANGPT4 comprises 242 amino acids and has a predicted molecularmass of 27.6 kDa. The apparent molecular mass of the protein isapproximately 38 kDa in SDS-PAGE under reducingconditions due to glycosylation.
Formulation Lyophilized from sterile PBS, pH7.4.
  1. Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
Storage Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
ReconstitutionA hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
MSTN / GDF8 Protein Description

Angiopoietin 4, also known as ANG-4 or ANGPT4, is a protein belongingto the angiopoietin family and is highly expressed inthe lung with much lower levels found in other tissues. Angiopoietin 4 / ANG-4 / ANGPT4 is a protein withimportant roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to anendothelial cell-specific tyrosine-protein kinasereceptor. The mechanism by which they contribute to angiogenesis is thought toinvolve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by thisgene functions as an agonist and is an angiopoietin. Angiopoietin 4 secreted ligand for the vascular endothelial restricted receptortyrosine kinase TEK,including phosphorylation of TEK,promoting angiogenic remodeling as well as vesselmaturation and stabilization,predominantly expressed in lung.

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