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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ApexBio/DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel/5mg/well/L1010
产品编号:L1010
市  场 价:¥45400.00
场      地:美国(厂家直采)
产品分类: 蛋白类>聚合物>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$2270.00
品      牌: ApexBio
公      司:ApexBio
公司分类:
ApexBio/DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel/5mg/well/L1010
商品介绍
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Molarity CalculatorDilution Calculator
DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel

Catalog No.L1010
SizePriceStockQty
5mg/well
$2,270.00
In stock

Tel: +1-832-696-8203

Email: sales@apexbt.com

Worldwide Distributors

Sample solution is provided at 25 µL, 10mM.

Click and Customize the Panelwith your own choices of compounds/size/quantities/chemical forms etc.

Publications citing ApexBio Products

Nature.2017 Jan 19;541(7637):417-420.
Nature.2018 Nov;563(7731):407-411.
Nature.2018 Jun 13.
Nature.2018 Jun 27.
Nature.2018 Mar 29;555(7698):673-677.
Nature.2017 Sep 7;549(7670):96-100.
Nature.2016 Apr 21;532(7599):398-401.
Science.2016 Aug 5;353(6299)594-8
Nat Nanotechnol.2017 Dec;12(12):1190-1198.
Nature Biotechnology.2017 Jun;35(6):569-576
Nat Med.2018 Sep 17.
Cell.2018 Dec 21. pii: S0092-8674(18)31561-7.
Cell.Available online 25 October 2018.
Cell.2018 Sep 27. pii: S0092-8674(18)31183-8.
Cell.2018 Jun 28;174(1):172-186.e21.
Cell.2018 Feb 22;172(5):1007-1021.e17.
Cell.2017 Nov 30;171(6):1284-1300.e21.
Cell.2017 Aug 17. pii: S0092-8674(17)30869-3.
Cell.2017 Jul 13;170(2):312-323
Nat Med.2018 Jan 29.
Nat Med.2017 Nov;23(11):1342-1351.
Cell.2017 Apr 6;169(2):286-300.
Cell.2015 Aug 27;162(5):987-1002.
Cell.2015 Feb 12;160(4):729-44.
Nature Medicine.2017 Apr;23(4):493-500.
Cancer Cell.2018 May 14;33(5):905-921.e5.
Cancer Cell.2018 Apr 9;33(4):752-769.e8.
Cancer Cell.2018 Mar 12;33(3):401-416.e8.
Cancer Cell.2017 Aug 14;32(2):253-267.e5.
Nat Methods.2018 Jul;15(7):523-526.
Cell Stem Cell.2018 May 3;22(5):769-778.e4.
Cell Stem Cell.2017 Nov 20. pii: S1934-5909(17)30375-2.

HTS Facility Partners

HTS Facility Partners

Featured Products of the Panel

Catalog No.Product NameSummaryTargetsCAS NumberSmiles
A3850TAK-242TLR 4 signaling inhibitorImmunology/Inflammation|TLR243984-11-4CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl
A3248BMS-345541IKK inhibitor,highly selectiveNF-κB|IκB/IKK547757-23-3CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl
A3628MLN120BIκB Kinase β InhibitorNF-κB|IκB/IKK783348-36-7CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4
B1585SC-514ATP-competitive IKK-2 inhibitor, orally activeNF-κB|IκB/IKK354812-17-2C1=CSC=C1C2=CC(=C(S2)C(=O)N)N
B3033Bay 11-7085NK-κB activation inhibitorNF-κB|IκB/IKK196309-76-9CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N
N1855AndrographolideNF-κB signaling InhibitorNF-κB|IκB/IKK5508-58-7CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O
A3891TriptolideIL-2/MMP-3/MMP7/MMP19 inhibitorNF-κB|NF-κB38748-32-2CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C
A4217QNZ (EVP4593)Potent NF-κB inhibitorNF-κB|NF-κB545380-34-5C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N
Download the Immunology/Inflammation-related Compounds Panel - XLSXDownload the Immunology/Inflammation-related Compounds Panel - SDF

Signaling Pathway

NF-κB Compare Products
IκB/IKK Compare Products
5-Lipoxygenase Compare Products

Advantages

  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

SolubilitySoluble in DMSOStorageDesiccate at -20°C
Packaging96 well plateFormPowder
General tipsFor obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping ConditionEvaluation sample solution : ship with blue iceAll other available size:ship with RT , or blue ice upon request

Background

A wide range of well-characterized bioactive molecules that covers various targets related to immunology/inflammation, including TLR, PLA2 and NF-κB etc. Facilitate your research towards the insights of cancer, inflammatory and autoimmune diseases etc. Applicable in cellular assays, animal models and drug screenings etc.

References

1. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innatereceptors in infection and immunity. Immunity. 2011 May 27;34(5):637-50.Abstract TLR(Toll-like receptor)-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs(pattern recognition receptors), such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. In this review, we will focus on the role played by TLRs in mounting protective immune responses against infection and their crosstalk with other PRRs with respect to pathogen recognition.
品牌介绍


ApexBio是用于生物学研究的肽和实验室试剂的主要提供商。我们在细胞凋亡,表观遗传学,癌症生物学等研究领域拥有广泛的产品线。Apexbio还提供定制服务,包括肽合成,抗体生产和测定开发。


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